Your choices determine your role in the world—either as a law-abiding "advocate" helping others or a "bandit" preying on fellow survivors.

Players can focus on PvE (killing zombies and bosses) or PvP (fighting other players for their gear).

The core plot revolves around scientific efforts to create a vaccine using stem cells from recently "revived" ghouls. This creates a high-stakes environment where players act as scavengers and "donors" of these biological samples.

The game takes place in the forests and towns of Colorado. An unknown virus has decimated the population, turning them into "zombies" or mindless mutants.