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: Activating this sole receptor triggers epithelial differentiation, which counteracts the "mesenchymal" (migratory) state of cancer cells. Significance : This makes

is the sole agonist capable of mimicking the growth-inhibitory and anti-migratory effects of All-trans-retinoic acid (ATRA). Sole.rar

In molecular biology, are nuclear receptors that mediate the effects of vitamin A (retinoic acid). Researchers often identify a specific subtype (like potentially impacting fertility.

: Mutations in this specific receptor render these cells "refractory" or unresponsive to regulatory signals, potentially impacting fertility. Sole.rar