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: Requires inpatient admission or prolongs an existing stay.
: Required to prevent one of the outcomes listed above. Required Reporting Information SAE Reporting and the IRB: Adverse Events in Drug Studies Sae__.mp4
: Sponsors have specific windows for notifying regulatory bodies like the FDA, often ranging from 7 to 15 calendar days depending on the event's severity and whether it was unexpected. : Requires inpatient admission or prolongs an existing stay
: The participant was at immediate risk of death at the time of the event. : The participant was at immediate risk of
: Results in a persistent or significant change to normal life functions.
This information pertains to the reporting of in clinical trials, a critical regulatory requirement for maintaining patient safety and data integrity. Core Reporting Timelines
An event is classified as "serious" if it meets one or more of the following criteria: : Regardless of the perceived cause.