Renal Failure Direct

Clinical Overview: Renal Failure (Kidney Failure) Renal failure occurs when the kidneys lose the ability to sufficiently filter waste products from the blood to sustain life. This condition can manifest as either , characterized by a sudden and often reversible decline in function, or Chronic Kidney Disease (CKD) , a progressive condition that may eventually lead to End-Stage Renal Disease (ESRD) . 1. Classification and Epidemiology

Approximately 850 million people worldwide (over 10% of the population) are affected by kidney disease. It is projected to become the fifth leading cause of death globally by 2050. 2. Pathophysiology and Causes renal failure

Classified into five stages based on the Estimated Glomerular Filtration Rate (eGFR) . A normal eGFR is above 60; levels below this for extended periods indicate progressive damage. Pathophysiology and Causes Classified into five stages based