The cause of the plague (often cited in scripts as a chemical agent meant to cripple China's economy).
Y: The Last Man, Vol. 7: Paper Dolls - Amazon.com
This is specifically Volume 7 of the trade paperback series, which follows Yorick's search for his fiancée in Australia. Key Themes for a Research Paper: Last Man
Shelley wrote this as a "roman à clef" reflecting her own feelings of isolation after the deaths of her friends (Lord Byron and Percy Bysshe Shelley).
A plague slowly wipes out humanity in the late 21st century, leaving only Lionel Verney. The cause of the plague (often cited in
How a world without men reorganizes its leadership and labor. 2. " The End of History and the Last Man " (Philosophy)
If this is for a political science or philosophy paper, you're likely dealing with Francis Fukuyama's 1992 book. Key Themes for a Research Paper: Shelley wrote
Fukuyama argues that Western liberal democracy is the "final form of human government" and the "end-point of mankind's ideological evolution".