It was designed to offer better accuracy than traditional metrics by combining cellular biomarkers with imaging data and physical disease characteristics. The Components of KBMP4
Documented meningeal lymphomatosis (spread to the brain or spinal cord membranes). It was designed to offer better accuracy than
High proliferation index (Ki67 ≥ 70%) on immunohistochemistry. B (Bulky): Physical presence of a tumor mass ≥ 7.5 cm. It was designed to offer better accuracy than