: The eldest daughter and social outcast, frequently used as the "punching bag" for the family's jokes.
: Conceived the show based on his college thesis films, The Life of Larry and Larry & Steve . He voices several lead characters, including the bumbling patriarch Peter , the genius baby Stewie , and the martini-swilling dog Brian .
: The teenage son, sharing his father’s lack of intelligence but possessing a hidden talent for art.
: The matriarch and voice of reason who occasionally reveals a darker, more impulsive side.