The most effective removal technique is never needing one. Using a standard user account instead of an administrator account for daily tasks, keeping a robust firewall active, and practicing "link skepticism" are your best defenses.
Use a reputable, non-resident scanner (like Malwarebytes) to catch threats that your primary antivirus might have missed. Effective Computer Virus Removal Techniques
Ensure your Operating System and all software are fully patched. The most effective removal technique is never needing one
No single antivirus program is perfect. For effective removal, use a "layered" strategy: keeping a robust firewall active