Atrophy Apr 2026

This is for informational purposes only. For medical advice or diagnosis, consult a professional. AI responses may include mistakes. Learn more Cellular and molecular mechanisms of muscle atrophy - PMC

Atrophy involves the wasting of tissues due to catabolic processes exceeding anabolic synthesis, commonly classified into disuse and neurogenic types in skeletal muscle, as well as cerebral atrophy in neurodegenerative conditions. Molecularly, this wasting is driven by ubiquitin-proteasome and autophagy-lysosome pathways, with emerging research focusing on the muscle-brain axis and the impact of cognitive offloading. For more detailed information, review the findings on NIH's PubMed Central at PMC . atrophy